2019年11月7日星期四

US scientists cultivated human heart tissue on spinach leaves

US scientists have successfully cultivated human heart tissue on spinach leaves, and managed to make it beat for up to three weeks.

Bioengineers Glenn Gaudette and Joshua Gershlak at Massachusetts Worcester Polytechnic Institute (WPI) led this research and their findings are valuable to a deadly medical problem: the lack of donor organs.

Scientists have long been trying different methods, such as 3-D printing, to create artificial organs. However, so far none of those methods has been successful.

One of the big problems in engineering heart muscle is getting blood flow to all of the cells.

Instead of creating minuscule blood vessels, researchers turned to the material that evolves in nature: spinach leaves, which have vessels that are similar to the blood vessels in a human heart.

They used detergent to wash away spinach cells. Cellulose, which is compatible to mammal cells, and intact leaf veins were left behind. Therefore, the frame of the leaves was reserved.

Then researchers seeded cardiac muscle cells into the vacancy left by spinach cells and after five days the muscle cells started to beat.


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